Before taking serdexmethylphenidate and dexmethylphenidate,
tell your doctor and pharmacist if you are allergic to serdexmethylphenidate, methylphenidate, dexmethylphenidate, any other medications, or any of the ingredients in serdexmethylphenidate and dexmethylphenidate capsules. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
tell your doctor if you are taking the following medications or have stopped taking them in the past 14 days: monoamine oxidase (MAO) inhibitors including isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). Your doctor will probably tell you not to take methylphenidate until at least 14 days have passed since you last took an MAO inhibitor.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: alpha blockers such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax, in Jalyn), and terazosin; angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), or trandolapril (in Tarka); angiotensin receptor blockers (ARBs) such as azilsartan (Edarbi, in Edarbyclor), candesartan (Atacand, in Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, in Azor, in Benicar HCT, in Tribenzor), and telmisartan (Micardis, in Micardis HCT, in Twynsta); beta blockers such as atenolol (Tenormin, in Tenoretic), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), propranolol (Inderal, Innopran, in Inderide), and timolol (Blocadren, in Timolide); calcium channel blockers such as diltiazem (Cardizem), nicardipine, nifedipine (Adalat, Procardia), and verapamil (Calan, Verelan, in Tarka); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft); venlafaxine (Effexor); and risperidone (Risperdal). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if anyone in your family has or has ever had an irregular heartbeat or has died suddenly. Also tell your doctor if you have recently had a heart attack and if you have or have ever had a heart defect, high blood pressure, an irregular heartbeat, hardening of the arteries, heart or blood vessel disease, or other heart problems. Your doctor will examine you to see if your heart and blood vessels are healthy. Your doctor will probably tell you not to take serdexmethylphenidate and dexmethylphenidate if you have a heart condition or if there is a high risk that you may develop a heart condition.
tell your doctor if you or anyone in your family has or has ever had depression, bipolar disorder (mood that changes from depressed to abnormally excited), or mania (frenzied, abnormally excited mood), or has thought about or attempted suicide. Also tell your doctor if you have or have ever had mental illness, or circulation problems in your fingers or toes.
tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking serdexmethylphenidate and dexmethylphenidate, call your doctor.
tell your doctor if you are breastfeeding. If you breastfeed while taking serdexmethylphenidate and dexmethylphenidate, monitor the breastfed infant carefully for agitation, weight loss, or poor feeding. Call your doctor immediately if the breastfed infant has any of these symptoms.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking serdexmethylphenidate and dexmethylphenidate.
you should know that serdexmethylphenidate and dexmethylphenidate should be used as part of a total treatment program for ADHD, which may include counseling and special education. Make sure to follow all of your doctor's and/or therapist's instructions.