Before taking lorcaserin,
tell your doctor and pharmacist if you are allergic to lorcaserin, any other medications, or any of the ingredients in lorcaserin tablets. Ask your pharmacist or check the patient information for a list of the ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications and vitamins you are taking or plan to take. Be sure to mention any of the following: bupropion (Aplenzin, Forfivo, Wellbutrin, Zyban); cabergoline; codeine (in some pain medications and cough medications); dextromethorphan (in cough and cold medications); flecainide (Tambocor); insulin and other medications for diabetes; linezolid (Zyvox); lithium (Lithobid); medications for erectile dysfunction, or mental illness; medications for migraine headaches such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); other medications for weight loss; metoprolol (Toprol); mexiletine; monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); odansetron (Zofran); propafenone (Rythmol); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine, paroxetine (Paxil), and sertraline (Zoloft); selective serotonin/norepinephrine reuptake inhibitors (SNRIs) such as duloxetine (Cymbalta) and venlafaxine (Effexor); tamoxifen (Soltamox); timolol (Blocadren); tricyclic antidepressants (TCAs) such as amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); and tramadol (Conzip, Ultram, Ryzolt). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with lorcaserin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
tell your doctor what herbal products and nutritional supplements you are taking, especially St. John's wort, tryptophan, and herbs or supplements for weight loss.
tell your doctor if you have or have ever had blood cell problems such as sickle cell anemia (a disease of the red blood cells), multiple myeloma (cancer of the plasma cells), or leukemia (cancer of the white blood cells); a condition that affects the shape of the penis such as angulation, cavernosal fibrosis, or Peyronie's disease;diabetes; heart failure, slow or irregular heartbeat, or other heart problems; or liver or kidney disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking lorcaserin, call your doctor immediately. Lorcaserin may harm your unborn baby.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking lorcaserin.
you should know that lorcaserin may cause drowsiness and difficulty paying attention or remembering information. Do not drive a car or operate machinery until you know how this medication affects you.